HYDROGEN SULFIDE SUPPLEMENTATION AS A POTENTIAL TREATMENT FOR PRIMARY MITOCHONDRIAL DISEASES

Primary mitochondrial diseases (PMD) are amongst the most common inborn errors of metabolism causing fatal outcomes within the first decade of life.With marked heterogeneity in both inheritance patterns and physiological manifestations, these conditions present distinct challenges for targeted drug therapy, where effective therapeutic countermeasur

Abstract Background Hurricanes can have catastrophic effects on coastal ecosystems.To minimize negative impacts of storms, animals may seek shelter in place, move to a nearby refuge, or evacuate long-distances.Crocodilians can be important predators in estuarine habitats, but little is known about how they respond to extreme weather events.We inves